PhD Position on ‘Neuromodulation and Arousal Regulation through Bio-/Neurofeedback'

100%, Zurich, fixed-term

In the newly established Brain-Body Regulation Lab at ETH Zurich (Department of Health Sciences and Technology), we focus on developing non-invasive (self-regulation) methods to modulate brain function during wake and sleep and on understanding how the brain interacts with other bodily functions. The majority of our studies are conducted in healthy volunteers; however, future projects will also involve patient cohorts. We are currently seeking a motivated and skilled PhD student to join our team.

Project background

This project focuses on neuromodulatory systems (and the locus coeruleus in particular), their role in regulating the brain arousal levels and effects on other bodily signals. By using a novel biofeedback approach based on our eye's pupil dynamics in combination with neuroimaging, electrophysiological, and respiratory recordings, we intend to understand and modulate these crucial brain functions and their effects on bodily physiology during wake and sleep. 

Job description

The successful candidate will work on designing and conducting human experiments using multimodal designs that investigate the link between central and peripheral arousal levels during wake and sleep. A central focus of the project will be using pupillometry (in combination with other (neuro) physiological recordings) to indirectly assess activity in arousal regulating systems in the brain and exploring their role in supporting brain and bodily functions through non-invasive interventions.

Your work will include:

  • Development of study designs and research questions
  • Configuration and integration of multimodal biosignal recording systems
  • Hands-on data acquisition using methods such as non-invasive electrophysiological, respiratory, and pupillometry recordings during sleep and wake in humans.
  • Advanced signal processing
  • Dissemination of research findings through scientific publications and presentations
  • Supervision of (BSc and MSc) students

The project provides a unique opportunity to combine and synchronize different physiological recordings including EEG, ECG, respiratory recordings and pupillometry. The successful candidate will be part of all aspects of scientific work making this an exciting and challenging position.

Profile

We are looking for a candidate with:

  • A Master’s degree (or nearing completion) in health sciences and technology, neuroscience, psychology, neurophysiology, biomedical engineering, or a related field
  • Programming experience (e.g., Matlab, Python)
  • Experience with at least one electrophysiological recording method or related experimental method listed above
  • The ability to design and conduct rigorous experiments in humans, with a particular emphasis on synchronizing data from multiple sources
  • Experience setting up complex biosignal recordings is an advantage
  • Strong communication skills, scientific curiosity, and a collaborative spirit
  • Being self-motivated, reliable, and organized
  • Being fluent in English; German language skills are an advantage

Workplace

Workplace




We offer

A fully funded PhD position (~4 years) in a great scientific and social environment at a world leading University (see below). The project will equally combine lab work and computational analysis of the acquired data and provides a great opportunity to establish a portfolio that covers all aspects of scientific work.

  • Your job with impact: Become part of ETH Zurich, which not only supports your professional development, but also actively contributes to positive change in society
  • We are actively committed to a sustainable and climate-neutral university
  • You can expect numerous benefits, such as public transport season tickets and car sharing, a wide range of sports offered by the ASVZ, childcare and attractive pension benefits
Working, teaching and research at ETH Zurich

We value diversity

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish.

Curious? So are we.

We look forward to receiving your online application with the following documents until June 12th 2025:

  • Curriculum Vitae including educational history, awards, etc
  • Research motivation statement of max. two A4 pages covering your interests, goals, experiences, and how they would relate to and fit with the proposed research domain and activities
  • Diplomas
  • Names and e-mail addresses of at least two references

Please note that we exclusively accept applications submitted through our online application portal. Applications via email will not be considered.

Starting date: Summer 2025 (or upon mutual agreement)

Questions regarding the position should be directed to Prof. Dr. Sarah Meissner by email sarah.meissner@hest.ethz.ch (no applications).

About ETH Zürich

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.