Joint Postdoc in Evolutionary Modeling
Organisms must adapt to many challenges over evolutionary time. Many traits differentiate alternately adapted populations, but many do not. Yet it is clear that to maintain traits may also require a substantial amount of evolution, as many core cellular processes are perturbed by environment. How the biophysical properties of proteins whose functions must be maintained affect the evolutionary dynamics of the underlying genes in real populations has not been extensively explored in population genetics. As a result, we miss information to interpret some of the patterns we observe in genome scans for selection. We seek to generate new population genetic models that incorporate what is known about biophysical properties of evolving proteins to understand how these play out long-term in populations as they adapt to novel habitats. Answering this will involve not only analyzing genomic data, but building new models to better understand how genes encoding proteins with specific biophysical constraints evolve in diverging populations.
Postdoctoral level independent mentored research in evolutionary / population genetic modeling. Preparations of presentations and manuscripts. Some mentoring of students and participation in practical and block course teaching. The position will be shared between the Widmer and Bomblies groups, and the researcher will have access to lab and office space, as well as computing facilities and resources.
The Widmer and Bomblies groups at ETH are seeking a joint postdoctoral fellow focused on evolutionary modeling. We seek an “out-of-the-box” thinker with established skills in evolutionary modeling and/or population genetics, experience with or desire to learn analytical skills with high-throughput sequencing, and a willingness to read widely and learn about protein biophysics and biochemistry to incorporate this into building realistic models. This person will be co-mentored by Professors Widmer and Bomblies at the ETH Zürich, and will be embedded in both lab groups.
We look forward to receiving your online application BY OCTOBER 31, 2021 with the following documents:
- Names of at least 2 referees
- Motivation letter that clearly describes why you are interested in this opportunity
Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.
Questions regarding the position (but not application materials) should be directed to Prof. Kirsten Bomblies: firstname.lastname@example.org
For more information about the research of the labs see: Bomblies lab, Widmer lab
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